Hongbo Zhang

Vice President of Research and Development

StoneWise (HITChem)

Short Biography

Zhang Hongbo, Ph.D. in Organic Chemistry from Nankai University, with over 10 years of experience in preclinical R&D of small molecule innovative drugs. He has participated in and advanced multiple projects from early discovery to clinical approval in China and the US as a medicinal chemistry expert or in a project management role. Currently, he serves as Vice President of Wangshi Wisdom Technology and Head of the New Drug Development Technology Service Department. He is responsible for the operational management of the company's new drug technology services department, as well as expanding related business in China and overseas. Additionally, within the company, he deeply participates as a technical expert in the development of AI-related molecule generation technologies for early small molecule discovery, and realizes the productization and commercial transformation of technical models.

Presentation Topic:  Development of CRBN Molecular Glue Library Combining AI and Structure Design: Oriented Towards High-Throughput Screening and Rational Design

• Key Challenges in CRBN Molecular Glue Library Development;
• Exploring the Chemical Space of CRBN Molecular Glues with Generative AI;
• Case Sharing: How to Discover Molecular Glues with Novel Structures;
• Comprehensive Platform Overview for Hit Compound Discovery and Optimization Services;.