Itsuro Nagase

Senior Vice President, Head of Primary Focus Lead – Targeted Protein Degradation

Astellas Pharmaceutical

Short Biography

Itsuro Nagase is Head of Primary Focus Lead, Targeted Protein Degradation at Astellas Pharma. He leads the strategy and portfolio development of protein degradation platforms, spanning discovery through clinical proof‑of‑concept. His work focuses on leveraging platform technologies to drive portfolio‑level decision making and to maximize the value of platforms and individual assets.
Itsuro graduated from Hokkaido University and earned a PhD in Veterinary Medicine. He has spent over 30 years at Astellas Pharma, gaining broad experience across research, clinical development, project leader and corporate strategy throughout his career.

Presentation Topic: Clinical Proof‑of‑Concept of Setidegrasib (ASP3082)

• Astellas’ strategy to strengthen its R&D pipeline and deliver meaningful value to patients

• Clinical proof‑of‑concept of Setidegrasib in advanced non‑small‑cell lung cancer and pancreatic cancer

• Beyond Setidegrasib: defining the next steps for targeted protein degradation