Program Overview
In recent years, targeted protein degradation (TPD) technology has emerged as a groundbreaking approach in drug discovery. By harnessing the ubiquitin-proteasome system or lysosomal pathways, protein degraders (e.g., PROTACs, molecular glues, and LYTACs) selectively induce the degradation of disease-related proteins, offering novel solutions for traditionally "undruggable" targets.
Although TPD technology has demonstrated broad application prospects in multiple fields, several challenges remain to be overcome. These include improving degradation efficiency and specificity, reducing off-target effects, and ensuring in vivo safety. Additionally, the clinical translation of TPD faces numerous hurdles, such as drug stability, pharmacokinetic properties, and potential long-term toxicity.
With several Degraders advancing into clinical trials, the industry urgently needs interdisciplinary collaboration to drive technological innovation and standardization. In Return, TPD2026 Targeted Protein Degradation Forum will bring together academia and industry leaders to explore cutting-edge advancements, technical bottlenecks, and future directions in TPD, providing strategic insights and a collaborative platform to accelerate the development of next-generation protein degradation therapeutics.
2026 Speaker Committee
Program Key Discussions
- The Application and Development Strategy of Targeted Protein Degradation Technology
- Novel Targeted Protein Degradation Technologies and Drug Discovery
- Cutting Edge Drug Design and Evaluation
- Discovery and Application of Novel Ligase Ligands
- Translational and Clinical Development
- CMC Development and Commercialization Strategies
- Development and Exploration of Next-Generation Targeted Protein Degraders
Who would Attend
Approximately 350 professionals are expected to participate in the TPD2025 Targeted Protein Degradation Forum in China. Participants are mainly from targeted protein degradation technology research, innovative drug development companies, research institutes. The main positions include:
- Management and Head of R&D
- Researchers of Universities and Scientific Research Institutions
- Early Stage Research, Technology Development and External Innovation
- Medicinal Chemistry Research
- Translational and Clinical Development
- Preclinical and Clinical Research
- CMC and Quality Control
- Investment and Project Management
- Business and Market Development
